BIOI611 lab

Welcome to BIOI 611! I’m excited to have you in this course, where we will delve into the fascinating world of transcriptomics and explore the intricacies of gene and transcript-level expression analysis.

This course focuses on the analysis of transcriptomics data, and specifically on the analysis of gene and transcript-level expression. Material covered includes transcript and gene expression estimation from RNA-seq data (short and long-read), basic experimental design and statistical methods for differential expression analysis, discovery of novel transcripts via reference-guided and de novo assembly, and the analysis of single-cell gene expression data (e.g., single-cell expression quantification, dimensionality reduction, clustering, pseudotime analysis). Prerequisite: BIOI 604. Core.